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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
26.97
Human Site:
S606
Identified Species:
37.08
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S606
G
G
K
G
S
G
K
S
T
L
A
K
A
I
C
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S606
G
G
K
G
S
G
K
S
T
L
A
K
A
I
C
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S604
G
G
K
G
S
G
K
S
T
L
A
K
A
I
C
Dog
Lupus familis
XP_532459
1267
140567
S590
G
G
K
G
S
G
K
S
T
L
A
K
A
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
S607
G
G
K
G
S
G
K
S
T
F
A
K
A
I
C
Rat
Rattus norvegicus
P46462
806
89330
L213
I
G
G
C
R
K
Q
L
A
Q
I
K
E
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
K571
A
V
L
L
T
G
P
K
G
S
G
K
T
T
V
Chicken
Gallus gallus
XP_418655
1290
143066
S614
G
G
K
G
S
G
K
S
T
L
A
K
A
I
C
Frog
Xenopus laevis
P23787
805
89193
Q212
D
I
G
G
C
R
K
Q
L
A
Q
I
K
E
M
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
L213
I
G
G
V
R
K
Q
L
A
Q
I
K
E
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
K208
D
D
I
G
G
C
R
K
Q
L
A
Q
I
K
E
Honey Bee
Apis mellifera
XP_397107
1069
120490
I476
Y
T
S
H
L
T
T
I
L
T
E
C
Q
L
A
Nematode Worm
Caenorhab. elegans
P54812
810
89622
Q217
D
L
G
G
V
R
K
Q
L
A
Q
I
K
E
M
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
T760
G
G
R
G
S
G
K
T
T
V
A
K
A
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
E222
K
Q
M
A
Q
I
R
E
L
V
E
L
P
L
R
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
P450
M
V
N
Y
L
T
S
P
I
I
A
T
P
A
I
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
E656
T
T
E
A
V
D
G
E
E
A
E
D
L
W
G
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
13.3
100
13.3
13.3
N.A.
20
0
13.3
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
20
100
13.3
26.6
N.A.
33.3
6.6
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
12
0
0
0
0
12
18
53
0
42
6
6
% A
% Cys:
0
0
0
6
6
6
0
0
0
0
0
6
0
0
42
% C
% Asp:
18
6
0
0
0
6
0
0
0
0
0
6
0
0
0
% D
% Glu:
0
0
6
0
0
0
0
12
6
0
18
0
12
12
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
42
53
24
59
6
48
6
0
6
0
6
0
0
0
6
% G
% His:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
6
6
0
0
6
0
6
6
6
12
12
6
36
6
% I
% Lys:
6
0
36
0
0
12
53
12
0
0
0
59
12
6
0
% K
% Leu:
0
6
6
6
12
0
0
12
24
36
0
6
6
12
0
% L
% Met:
6
0
6
0
0
0
0
0
0
0
0
0
0
12
12
% M
% Asn:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
6
6
0
0
0
0
12
0
0
% P
% Gln:
0
6
0
0
6
0
12
12
6
12
12
6
6
0
0
% Q
% Arg:
0
0
6
0
12
12
12
0
0
0
0
0
0
0
6
% R
% Ser:
0
0
6
0
42
0
6
36
0
6
0
0
0
0
0
% S
% Thr:
6
12
0
0
6
12
6
6
42
6
0
6
6
6
0
% T
% Val:
0
12
0
6
12
0
0
0
0
12
0
0
0
6
18
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% W
% Tyr:
6
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _